Accumulating evidence has demonstrated that interference with Axl expression and/or its activity results in inhibition of cell proliferation [36,37], angiogenesis [38], migration, and invasion in cancer cells [39,40], and results in a decrease in chemoresistance [41] and an increase in chemosensitivity [12,41] and the induction of apoptosis [11,12,20,21] in various cancer types. Here, AXL is linked to cancer.