Bufalin has been shown to inactivate Na+/K+-ATPase in bladder carcinoma cells [52], reduce the expression of human telomerase reverse transcriptase in colorectal, pancreatic, and oral cancer cells [27,53], and down-regulate Mcl-1 expression in NSCLC cells [29,54]. Here, MCL1 is linked to non-small cell lung carcinoma.