There were significant differences between the CAD and the normal groups in sex, age, smoking, hypertension, diabetes, HDL-C, non-HDL-C, non-HDL-C/HDL-C, hsCRP, TnI, CK-MB, pro-BNP, and the use of statins (P < 0.05). The gene discussed is NPPB; the disease is Hypertension.