Several proteins, including a number of heat-shock proteins, HNRNP-A2/B1, CUGBP1, lamin-A/C and MBP were found to localize with ubiquitin-positive inclusions in CGG-expressing Drosophila, KI mouse model and FXTAS patients. This evidence concerns the gene HNRNPA2B1 and fragile X-associated tremor/ataxia syndrome.