NFIB was significantly downregulated in 22 unique analyses across different breast cancer subtypes in 10 different databases including TCGA, Curtis (Curtis et al., 2012), Ma 4 (Ma et al., 2009), Zhao (Zhao et al., 2004), Turashvili (Turashvili et al., 2007), Sorlie (Sorlie et al., 2001), Richardson2 (Richardson et al., 2006), Sorlie2 (Sorlie et al., 2003), Perou and Gluck (Gluck et al., 2012; Perou et al., 2000). The gene discussed is NFIB; the disease is breast carcinoma.