In the previous research of this study, mice were immunized with purified recombinant EGFR to produce an EMab-134 monoclonal antibody (mAb; IgG1, kappa), which reacted with the endogenous EGFR of oral cancers in flow cytometry, Western blotting, and immunohistochemistry (12). The gene discussed is EGFR; the disease is lip and oral cavity carcinoma.