As shown in Fig.6, before liver cancer treatment, the TGF-β1 and IL-10 concentrations were positively correlated with the percentage of CD4+CD25+ CD127lowTregs in patients with HCC respectively ((r = 0.526, P = 0.017; r = 0.546, P = 0.013). This evidence concerns the gene IL10 and hepatocellular carcinoma.