KLRK1 and acute lymphoblastic leukemia: NKG2D and DNAM-1 receptors as well as the NCRs have been reported as important for the targeting of acute and chronic myeloid leukemias (AML,CML) blasts, acute lymphoblastic leukemia (ALL) [30,51,52,54,55], multiple myeloma [53] while the role of DNAM-1 receptor seems to be central in targeting freshly isolated myeloiddysplastic syndrome (MDS) blasts [56].