It has been reported that human IL-8, the murine KC analogue, has the capacity to retain DCs in the tumor, preventing trafficking to lymphoid organs for antigen presentation.44 Here, we found that in vivo, i.t.-delivered VVL15∆N1L was able to enhance the percentage of DCs in murine spleens, but further analysis of their phenotype would be important for translation of this therapy. The gene discussed is CXCL8; the disease is neoplasm.