On the contrary, serum CTGF levels in RA patients (123.5 pg/ml, 95%CI 94.08–152.84 pg/ml) were remarkably higher than those in normal persons (81.14 pg/ml, 95% CI 68.24–94.04 pg/ml) (Fig. 1d). The gene discussed is CCN2; the disease is rheumatoid arthritis.