In AML‐MRC, mutations in the following genes are found: ASXL1 (21%‐35%), TP53 (22%), RUNX1 (15%‐17%), TET2 (15%), IDH1 or IDH2 (25%), DNMT3A (8%‐9%), NPM1 (8%), and FLT3 (2%‐7%). The gene discussed is RUNX1; the disease is acute myeloid leukemia.