For example, DUXAP8 function as an oncogene and promote cell proliferation and invasion in multiple types of malignancies including non‐small cell lung cancer, renal cell carcinoma, colorectal cancer, and oesophageal squamous cell cancer34, 35, 36, 37; DSCR 8 acts as a molecular sponge for miR‐485‐5p and activate Wnt/β‐catenin signal pathway in hepatocellular carcinoma38; TPT1‐AS1 promotes tumorigenesis and metastasis in cervical cancer and epithelial ovarian cancer.42, 43. Here, DUXAP8 is linked to hereditary clear cell renal cell carcinoma.