As for patients with separate genetic alterations are concerned, Figure 1A indicated that the MLL‐R and FLT3‐ITD mutation's presence was associated with poorer prognosis while CBF‐AML (AML1/ETO or CBFβ/MYH11) was with better prognosis in the total cohort. The gene discussed is RUNX1; the disease is acute myeloid leukemia.