NOS1 and Fabry disease: To further investigate whether the regulation of gastric motility in FD rats by EA is dependent on the NMDAR-NO-cGMP pathway, MK-801, L-NAME, or MB was injected into the bilateral hippocampi of FD rats to block NMDAR, nNOS, or sGC, respectively, and gastric motility was recorded with a gastrointestinal pressure sensor.