DLG4 and Alzheimer disease: Research has shown that L-3-n-butylphthalide, an extract from the seeds of Apium graveolens (Chinese celery), increased the expression of PSD95 and SYN, attenuated the development of Aβ plaques and neuroinflammatory responses, promoted hippocampal neurogenesis, and improved behavioral recovery in aged AD mice [47].