ATXN1 and cerebellar degeneration: The lack of cerebellar degeneration in the young SCA1 mice, our correlational analysis and the fact that the mice with cerebellar-specific degeneration exhibit a number of opposite abnormalities (lack of immobility in the FST and MWM, reduced thigmotaxis in the OF and higher relative times in the open arms in the EPM)51–55 suggest that the behavior of the SCA1 mice may be relatively independent of motor deficits and cerebellar degeneration.