TNF and pleurisy: Furthermore, LLLT at 780 nm (7.7 J/cm2) suppressed IL-6 expression in a rat model of collagenase-induced tendinitis [49]; LLLT at 660 nm significantly reduced IL-6 and TNF-α expression in a rat model of carrageenan-induced pleurisy [50]; and LLLT at 660 nm (8 J/cm2) reduced the expression of inflammatory markers such as IL-1β, IL-6, and TNF-α in LPS-stimulated human adipose-derived stem cells [51].