MCM3 and hepatocellular carcinoma: We found that silencing MCM3 expression suppressed Huh7 and SK-Hep-1 cell proliferation according to CCK-8 assays and reduced the percentage of S-phase cells according to EdU-incorporation assays (Figure 7) but had no effect on the migration and invasion of HCC cells (Supplementary Figure 6A–6C and Supplementary Figure 6E).