The P10 hDPSC transplantation improved CCl4-induced liver fibrosis as indicated by the markedly suppressed area of fibrous tissue-deposition and the degree and expression of Col1a1 in the P10 hDPSC-transplanted group by Picrosirius Red staining, Ishak scoring, and qRT-PCR (Fig. 8d–g). This evidence concerns the gene COL1A1 and Hepatic fibrosis.