GRB2 and schizophrenia: For example, rs1130354 within the 3′-UTR of human dopamine receptor D2 (DRD2) alters miR-326-mediated expression regulation [39], rs550067317, located in the 3′-UTR of ephrin B2 (EFNB2), affects miR-137-mediated repression of EFNB2 expression [40] as well as rs7219 within 3′-UTR of GRB2 alters the expression of GRB2 by affecting miR-1288-mediated inhibition [41], thereby affecting the risk or progression of schizophrenia.