On the other hand, MSC in co-culture with MM cells showed up-regulation of several chemokine ligands (CXCL6, FC = 3.66; CXCL8, FC = 8.17; CXCL9, FC = 3.09; CXCL10, FC = 2.85; CCL2, FC = 4.56 and CCL7, FC = 15,62) reported to regulate cell trafficking and migration of immune cells [[31], [32], [33]], and interleukins (IL-7, FC = 2.43; IL-10, FC = 13.83; IL-22, FC = 3.37; IL-32, FC = 3.06) with immuno-modulatory properties [[34], [35], [36], [37]]. Here, CCL2 is linked to Miyoshi myopathy.