It is possible that TSLP produced by epithelial cells when exposed to exogenous stimuli acts on innate immune cells such as dendritic cells (DC), mast cells, eosinophils, and natural killer T (NKT) cells, which have an important role in the early stage of inflamation.24, 25 By contrast, the role of TSLP and TSLP receptors in bone and cartilage diseases has not been elucidated until recently. Here, TSLP is linked to cartilage disease.