MYORG and memory impairment: MYORG patients showed reduced verbal fluency and poor verbal reasoning in the first year of disease (cases 1 and 3), mild memory impairment (case 2, MMSE 27/30) with progression over the following years (case 7, Montreal Cognitive Assessment 21/30 and case 8, MMSE 23/30) to a diagnosis of dementia (case 5).