XIST and neoplasm: Notably, 10 of the lncRNAs showed significantly different expression between tumor and normal liver samples (P < 0.05, FC > 2.0) while the remaining 10 could not be identified by DEA (P < 0.05, FC > 2.0, or FC < 0.5), including NEAT1 (ranked 5th by CLING) and XIST (ranked 11th by CLING), which have been verified as LIHC-associated lncRNAs in recent literature (Guo et al., 2015; Zhuang et al., 2016).