Compared with the healthy samples, the expression of METTL3, HNRNPC, WTAP, KIAA1429, YTHDF2, and YTHDF1 was upregulated, while the expression of ALKBH5, YTHDC2, and FTO was downregulated in the GBM samples (Figures 1C,D). The gene discussed is FTO; the disease is glioblastoma.