Next, we addressed whether the presence of antigen (30) can induce the synergistic effect with NLGP, but detected no synergistic effect for both soluble tumor cellular lysate and necrotic antigen (Figures S6EA,B) in respect to MHC-I expression, but an upsurge of CD8+ T cell proliferation (Figure 6G) with IL-2 and IFN-γ production (Figure 6H) was found in antigen + NLGP group compared to the NLGP group when these DCs were cocultured with CD8+ T cells. This evidence concerns the gene IL2 and neoplasm.