NDUFS5 and Alzheimer disease: The top ranked AD-associated blood DMPs were located in DAPK1, GAS1, and NDUFS5. Furthermore, epigenetic age acceleration was shown to be associated with AD neuropathological markers such as neuritic plaques, diffuse plaques, and amyloid load in the dorsolateral prefrontal cortex (Levine et al., 2015b).