In contrast, mice vaccinated with lipidated TLR7/8 agonists UM-3003, UM-3005 or UM-3004 exhibited primarily a Th1 influenza-specific response in mice (Figures 3A,B; flow gating and example cytokine staining shown in Figure S2; low dose adjuvant T cell responses shown in Figure S3) which correlates with the IgG2a biased antibody responses also elicited by these adjuvants (see Figure 2). This evidence concerns the gene TLR7 and influenza.