TLR7 and influenza: Conversely, influenza-specific IgG2a was significantly increased in the majority of groups that contained a lipidated TLR7/8 agonist (Figure 2C): all groups adjuvanted with UM-3005, all groups adjuvanted with high dose lipidated TLR7/8 agonist plus 601, as well as high dose UM-3003 alone, and low dose UM-3004 alone.