In both SSc-PF and IPF lung samples, the expression levels of IGFBP2, IGFL2, and IL6 were significantly increased compared to NL (Figures 7A–C), and TLR8 was noticeably decreased in SSc-PF lungs, albeit not significantly (Figure 7D). The gene discussed is IGFBP2; the disease is pemphigus foliaceus.