SSc-PF is diffuse and displays inflammatory cell infiltration of the alveoli, interstitium and peribronchiolar tissues along with excessive proliferation of fibroblasts leading to extensive deposition of various extracellular matrix (ECM) proteins by mesenchymal cells, such as collagen type I and III, fibronectin and tenascin (2, 3). Here, TNC is linked to systemic sclerosis.