Specifically, in the SSc-PF “cytokine-cytokine receptor interaction” pathway under TNF Family (Supplementary Figure 8), TNFSF14-associated perturbation (labeled LIGHT) that leads to upregulation of LTBR, HVEM, and DCR3 was not observed in IPF (Supplementary Figure 10). The gene discussed is TNF; the disease is idiopathic pulmonary fibrosis.