Compared with the WT group, the expression of APP in the DMSO-treated AD group was significantly increased (Newman–Keuls test; p < 0.001, Figures 4G,H), whereas the treatment with DHA protected against the increase (+169.39% compared to WT, p < 0.001; +23.61% compared to AD, p < 0.01; Figures 4G,H). This evidence concerns the gene APP and Alzheimer disease.