Numerous investigations have been conducted on TOCP toxicity, which include various mechanism studies such as acetyl cholinesterase inhibition, neuropathy target esterase inhibition, or γ-aminobutyric acid antagonization (Lorke et al., 2017) in the neural system (Craig and Barth, 1999; Zhang et al., 2007), immune system (Foil et al., 1980; Brinkerhoff et al., 1981), or reproductive system (Xu et al., 2016), but consensus regarding this topic has not been reached. Here, ACHE is linked to neuropathy.