LRRK2 and infection: Leucine-rich repeat kinase 2 has also been genetically linked to Leprosy, a chronic dermato-neurological disorder caused by long-term infection with Mycobacterium leprae. Based on the clinical symptomology resulting from bacterial load and individual immune responses, leprosy acts as a spectrum of disease ranging from paucibacillary to multibacillary subtypes (Gaschignard et al., 2016).