Functions of these predicted target genes significantly enriched in the processes related with metabolic, biosynthetic, transcriptional and protein modification etc., biological regulatory mechanisms were integrated in several main KEGG pathways, most of which are cancer-related pathways, such as Ras signaling pathway, Hippo signaling pathway, ErbB signaling pathway, other types of O-glycan biosynthesis etc. These pathways regulate cell proliferation, adhesion, migration, differentiation, evasion and angiogenesis 28-31. Here, EGFR is linked to cancer.