To identify the mechanisms of MIAT in treating DR by HUMSCs, we studied the effects of HUMSCs on the expression of MIAT, proinflammatory cytokines and the microangiopathy in diabetic retina after tail-vein injection of HUMSCs by using STZ-induced diabetic rat models; and the correlation between MIAT and proinflammatory cytokines. The gene discussed is MIAT; the disease is diabetes mellitus.