In the correction for multiple comparison of factors associated with PD-L1/L2 status, pathological stage (multivariate OR: 0.59; 95% CI: 0.36–0.95; P = 0.030), and tumour-infiltrating lymphocytes (multivariate OR: 0.62; 95% CI: 0.38–0.99; P = 0.048) were significantly associated with both PD-L1- and PD-L2-negative groups. This evidence concerns the gene CD274 and neoplasm.