LEP and anorexia nervosa: Thus, the aims of this study are twofold: 1) to replicate the original study performed by Exner et al. 19, and to compare the efficacy of leptin and heightened Ta in SIH model in order to determine if housing temperature and not leptin plays a critical role in the regulation of semi-starvation induced hyperactivity in rats, which may be of relevance for the management of hyperactivity in anorexia nervosa in humans.