TNF and infection: MAYV infection induced acute production of several pro-inflammatory molecules in the spleen such as IL1-β (Fig. 2a) and IL-6 (Fig. 2b) from days 1 to 7 of infection; IFN-γ (Fig. 2c) from days 1 to 5 and finally, TNF-α (Fig. 2d) at the early time-points of 1 and 3 days post-MAYV inoculation.