Excinuclease UvrABC ATPase subunit (P value = 0.022, FC(P/H) = 16.3) and ATP-dependent DNA helicase RecQ (P value = 0.021, FC(P/H) = 3.29) related to DNA repair and SOS response were more abundant in the gut microbes of the CRC patients than the healthy crowds, Fig. 4b. The gene discussed is DNAH8; the disease is colorectal carcinoma.