TGM2 and neurodegenerative disease: Non-functional and dysregulated TGase2 is related to various human diseases, such as celiac disease [33], inflammatory disease [34], many types of cancers [3,35,36,37,38], tissue fibrosis [39], diabetes [40], pulmonary hypertension by fibrogenic remodeling [41], and neurodegenerative diseases [42,43,44].