Moreover, the molecular mechanisms were confirmed through a p53/phosphoinositide 3-kinases (PI3K)/mammalian target of rapamycin (mTOR) mechanism and an endoplasmic reticular stress/extracellular signal-regulated kinases (ERK)1/2 pathway in neuroblastoma cells and glioblastoma cells, respectively [13,14]. The gene discussed is MTOR; the disease is glioblastoma.