TGFB1 and pulmonary fibrosis: Specific integrin receptors, i.e., αvβ6 (in epithelial cells and fibroblasts) and αvβ8 (in Treg) exhibit the potential to recognize the TGF-β1 LAP, leading to activation of mature TGF-β1 in the context of pulmonary fibrosis or immune suppression [16,22].