Most of the remarkable nodes in the modules with a high degree of connectivity (viz., CCR2, CD80 (B7-1), TLR4, TLR7, and IL-10 in LUAD; and CSF1R, CCL2, and CCR1 in LUSC) were reported to be related to proliferation, migration, invasion, and immune tolerance in NSCLC [28–34]. This evidence concerns the gene CD80 and non-small cell lung carcinoma.