MALAT1 and neoplasm: Next, we found that subcutaneous inoculation of mixture of MALAT1-enriched exosomes with SW480 cells into nude mice promoted tumor growth and both the phosphorylation levels of cellular signals and fucosylation levels were increased in the exsomes-treated tumor tissues compared with those in the controls; However, MALAT1-knockdown exosomes failed to improve the fucosylation and phosphorylation levels of tumor tissue compared to control (Fig. 6e, f).