FAM225A and nasopharyngeal carcinoma: Moreover, bioinformatic analysis found two RRACU m6A sequence motifs in the last exon (position 2808 and 5460) of FAM225A. Subsequent functional assay showed METTL3-induced m6A modification of FAM225A improved its transcripts stability, which may partially account for the upregulation of FAM225A in NPC.