CD44 and endothelial dysfunction: While insights into the role of protein N-glycosylation in regulating inflammation have primarily focused on circulating immune cells (e.g. CD44 and other selectin ligands on neutrophils and T-cells [10,21,29], relatively little attention has been paid to the impact N-glycans may have on the function of endothelial adhesion molecules in diseases mediated by endothelial dysfunction.