AKT1 and cancer: The DEGs functional enrichment analysis indicated that the main pathways were associated with immune response and cancer (e.g., cytokine-cytokine receptor interaction, Human immunodeficiency virus 1 infection, focal adhesion, proteoglycans in cancer, and PI3K-Akt signaling pathway), which are in agreement with findings that immune response and cancer progression exhibit crosstalk and interact with each other [37].