There are several factors that may influence the thymus histological patterns: diabetes,46 infections,34 malnutrition,35 and age.16, 18 It is well‐described that the thymus suffers involution throughout the life of the animal accompanied by the reduction of the cortex.16, 18 Laminin, in turn, correlated inversely with the cortex/medulla ratio. The gene discussed is LAMB2; the disease is malnutrition.