We checked the expression profiles of 299 pan‐cancer‐related driver genes [56] in gastric tumorigenesis and found consistent differentially expressed driver genes in GPLs and EGC, including BCL2L11, RET, ALB, GRIN2D, and BRCA1. BCL2L11, which has been considered to act as an apoptotic activator, showed a significant decrease in gastric lesions [57]. This evidence concerns the gene BCL2L11 and cancer.