The expression of Prx-SO3 is highly increased in HCC of HBx Tg mice as compared to WT mice, as well as in dysplasia and hepatocellular adenoma (HCA) of HBx Tg mice, while pAkt and c-myc expressions were increased from earlier stage of tumorigenesis (Fig. 1), suggesting more severe oxidative stress in HCC. Here, MYC is linked to hepatocellular carcinoma.