There is no significant correlation between FGL2 and other genes implicated in lung adenocarcinoma such as EGFR, KRAS, TP53, STK11, NF1, and KEAP1. We speculated that FGL2 might indirectly affect those genes in lung adenocarcinoma by changing the immune status in the tumor environment. This evidence concerns the gene NF1 and lung adenocarcinoma.