GPC-1 is a member of heparin sulfate proteoglycans family, its overexpression has been reported to be involved in angiogenesis and tumor growth in pancreatic, cancer, glioma and breast cancer [41]; its prognostic role has been investigated in a study including 178 PDAC patients from the Cancer Genome Atlas (TCGA) and samples from 186 pancreatic cancer patients. The gene discussed is GPC1; the disease is neoplasm.